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Magic-mushroom drug can treat severe depression, trial suggests

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"A drug based on a compound in hallucinogenic mushrooms can improve the symptoms of severe depression for up to 12 weeks, a trial shows. A 25mg tablet of psilocybin puts patients in a dreamlike state, making psychological therapy more likely to succeed. But the short-term side-effects could be frightening and support must always be on hand, the researchers said. Experts say larger studies with a much longer follow-up are still needed. An estimated 100 million people worldwide have serious clinical depression that does not respond to any available treatments - 30% attempt suicide. After one 25mg dose of Comp360 psilocybin, alongside psychotherapy: - one in three were no longer diagnosed as depressed at three weeks - one in five saw a significant improvement at 12 weeks Study author and consultant psychiatrist Dr James Rucker said the drug was thought to have "a direct action on the brain, putting it into a more flexible state and providing an window of opportunity for therapy"." 11/03/22 https://www.bbc.com/news/health-63475630

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psilocybin

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depression

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treatment

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hallucinogenic

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